Product Name: C-QAS 20%

Type: Oral Liquid Solution - Nutraceutical (Vitamin C Supplement)

COMPOSITION

Each liter contains:

• Ascorbic Acid (Vitamin C) ...... 20% w/v (200 g per liter)

DESCRIPTION

C-QAS 20% is a concentrated liquid vitamin C supplement specifically formulated for poultry. Vitamin C (ascorbic acid) is a water-soluble vitamin that plays a crucial role in numerous physiological functions, including antioxidant defense, immune response, and stress management .

Although poultry can synthesize vitamin C endogenously, their production becomes insufficient under stress conditions such as high environmental temperatures, vaccination, or disease challenge due to increased metabolic demands and excessive reactive oxygen species (ROS) formation . Supplementation with vitamin C helps meet these elevated requirements and supports optimal health and performance .

MECHANISM OF ACTION

Antioxidant Activity:

• Acts as a potent antioxidant, scavenging free radicals and reactive oxygen species (ROS) generated during stress and infection
• Protects cellular membranes from oxidative damage
• Helps stabilize the action of vitamin E and other antioxidants

Immune System Support:

• Enhances immune function and disease resistance
• Promotes antibody production and phagocytic activity
• Supports the integrity of mucous membranes and skin

Stress Management:

• Reduces stress hormone (corticosterone) levels during heat stress
• Supports energy metabolism and adrenal function
• Helps maintain physiological homeostasis during environmental challenges

Metabolic Functions:

• Participates in collagen synthesis, supporting connective tissue integrity
• Facilitates iron absorption and plays a role in red blood cell formation
• Involved in the synthesis of steroid hormones and neurotransmitters

BENEFITS & INDICATIONS

C-QAS 20% is indicated for the management of stress and support of overall health in poultry .

Heat Stress Management:

• A 2025 meta-analysis of 35 studies confirmed that vitamin C supplementation significantly improves body weight (BW) and average daily gain (ADG) in broilers under heat stress (p = 0.003 and p = 0.001, respectively)
• Feed conversion ratio (FCR) is significantly improved with vitamin C supplementation (SMD = -0.529, p = 0.001)
• Vitamin C decreases serum triglyceride (p = 0.001), cholesterol (p = 0.001), and blood glucose (p = 0.02) concentrations in heat-stressed broilers
• A 2025 study demonstrated that vitamin C supplementation (200 mg/kg) combined with early feed withdrawal significantly improves growth performance, antioxidant capacity, and stress resilience in heat-stressed broilers

Immune Support:

• Has a positive influence on the immune system, promoting normal immune function
• Helps maintain healthy cells and tissues
• Supports recovery during and after disease challenges

Vaccination Support:

• Reduces post-vaccination stress and supports antibody response
• Recommended during vaccination periods to minimize stress-related performance losses

General Health Maintenance:

• Promotes energy metabolism and overall vitality
• Supports normal growth and development
• May improve eggshell quality during hot weather conditions

DOSAGE & ADMINISTRATION

C-QAS 20% is administered via drinking water. For optimal results, fresh medicated water should be prepared daily.

Recommended Dosage:

• Poultry (Broilers, Layers, Breeders, Turkeys, Ducks, Geese): 0.5 - 1.5 ml per liter of drinking water for 3-5 consecutive days
• Alternative Dosage: 1 ml per 1-2 liters of drinking water for general stress management
• Severe Stress (Heat Wave, Disease Recovery): 2 ml per liter of drinking water for the first 24-48 hours

Recommended Usage Periods:

• Heat Stress: Administer during periods of high ambient temperature; continue throughout the hot period
• Vaccination: Administer 1-2 days before and 2-3 days after vaccination
• Disease Recovery: Administer during and for 3-5 days after antibiotic treatment
• Transport/Handling: Administer 1-2 days before and on the day of transport

Administration Guidelines:

• Calculate total daily water consumption based on flock size, age, and environmental temperature
• Dissolve the required amount of C-QAS 20% directly into the drinking water tank or mixing system
• For use in automatic water proportioners, adjust settings according to manufacturer specifications
• Prepare fresh medicated water daily; discard any unused solution after 24 hours
• For best results during heat stress, administer during the hottest parts of the day (midday to early afternoon)

SCIENTIFIC EVIDENCE

2025 Meta-Analysis Findings:

• A comprehensive meta-analysis of 35 studies (1985-2023) published in January 2025 confirmed that vitamin C supplementation under heat stress significantly improves broiler performance
• Body weight (BW) increased by 0.339 SMD (p = 0.003) and average daily gain (ADG) increased by 0.381 SMD (p = 0.001)
• Feed conversion ratio (FCR) improved significantly (SMD = -0.529, p = 0.001)
• Vitamin C decreased triglyceride (SMD = -0.527, p = 0.001), cholesterol (SMD = -0.976, p = 0.001), and blood glucose (SMD = -0.734, p = 0.02) concentrations
• The recommended dosage based on this meta-analysis is 250 mg/kg of feed for broilers under heat stress

2025 Synergistic Effect Study:

• A study published in October 2025 demonstrated that combining vitamin C supplementation (200 mg/kg) with early feed withdrawal produced superior stress-mitigating effects in heat-stressed broilers
• The combination significantly improved growth performance, enhanced hepatic antioxidant enzyme expression, and reduced stress biomarkers
• Economic efficiency indicators were significantly improved with vitamin C supplementation

STORAGE & PRECAUTIONS

• Store in a cool, dry place below 25°C, protected from direct sunlight
• Vitamin C is a fragile molecule that is easily destroyed in neutral or alkaline solutions, at elevated temperatures, and upon exposure to oxygen
• Prepare fresh medicated water daily to ensure maximum potency
• Do not store medicated water for extended periods; stability decreases over time
• Avoid mixing with alkaline substances or water with high mineral content
• Keep out of reach of children
• Shake well before use
• Use within 28 days after first opening

Target Species: Poultry (Broilers, Layers, Breeders, Turkeys, Ducks, Geese, Quail)

Pack Sizes: 1 Liter, 5 Liter HDPE containers

PRODUCT SUMMARY
C-QAS 20% Liquid Nutraceutical Ascorbic acid (Vitamin C) 20% w/v Poultry 1L,5L

FOR VETERINARY USE ONLY