Comprehensive electrolyte and osmolyte supplement for poultry containing betaine, sodium chloride, magnesium chloride, potassium chloride, calcium chloride, and menthol. Provides rapid rehydration, electrolyte balance, and cooling relief during heat stress, diarrhea, and disease recovery.
Product Name: MENTAQAS.PLUS
Type: Oral Liquid Solution - Electrolyte & Osmolyte Supplement
COMPOSITION
Each 100 ml contains:
- Betaine ...... 100 g
- Sodium Chloride ...... 20 g
- Magnesium Chloride ...... 10 g
- Potassium Chloride ...... 8 g
- Calcium Chloride ...... 40 g
- Menthol ...... q.s. to 1 liter
DESCRIPTION
MENTAQAS.PLUS is a comprehensive electrolyte and osmolyte supplement specifically formulated for poultry to combat heat stress, dehydration, and electrolyte imbalance. This innovative formulation combines the osmoprotective properties of betaine with a balanced electrolyte profile and the unique cooling effects of menthol .
Exposing broilers to high temperatures increases water and electrolyte (K⁺ and Na⁺) excretion, which negatively affects heat dissipation capacity and acid-base homeostasis, resulting in losses in growth performance . This product is designed to address these challenges through a multi-faceted approach.
MECHANISM OF ACTION
Betaine (Osmolyte & Methyl Donor):
- Acts as an organic osmolyte to maintain cellular water and ion balance, preventing dehydration and osmotic inactivation during heat stress
- Functions as the most efficient methyl group donor, influencing various metabolic pathways
- Improves water retention at the cellular level; studies show betaine supplementation at 500 mg/L improved body weight gain in heat-stressed broilers during the first 4 days of heat exposure
- May promote beneficial intestinal microbes against osmotic variations, improving microbial fermentation activity
Electrolytes (Sodium, Potassium, Magnesium, Calcium):
- Restore electrolyte balance lost during heat stress, diarrhea, or dehydration
- Sodium and potassium maintain acid-base balance; studies show electrolyte-betaine supplements in water increase K⁺ and Na⁺ retention
- Calcium supports muscle function and eggshell quality; magnesium aids in enzyme function and stress reduction
- The combination of electrolytes with betaine improves feed conversion ratio (FCR) and enhances water consumption in heat-stressed birds
Menthol (Cooling Agent):
- Activates transient receptor potential melastatin 8 (TRPM8) channels, triggering a cooling sensation typically perceived at temperatures below 15°C
- Demonstrates antimicrobial, anti-inflammatory, and antioxidant properties that support overall health
- May help reduce rectal temperature in heat-stressed birds; studies show in ovo feeding of 15 mg menthol significantly decreased rectal temperatures after heat stress exposure
- Potential to mitigate heat stress through both physiological cooling and appetite-modulating properties
BENEFITS & INDICATIONS
MENTAQAS.PLUS is indicated for the management of heat stress, dehydration, and electrolyte imbalance in poultry .
Heat Stress Management:
- Provides cooling relief through menthol's TRPM8 activation
- Betaine helps maintain cellular hydration and osmotic balance
- Electrolytes restore acid-base balance disrupted by panting and heat stress
- Studies show electrolyte-betaine supplements improve FCR and enhance water consumption during high-temperature conditions
Dehydration Support:
- Rapidly regulates water-electrolyte balance and prevents electrolyte loss
- Recommended during illnesses, particularly those associated with diarrhea
- Supports recovery during convalescence and post-disease states
Stressful Conditions:
- During transport, handling, and flock rearrangements
- During vaccination periods to minimize stress-related performance losses
- During periods of intense physical exertion or high stocking density
Gut Health Support:
- Betaine promotes intestinal microbial activity and gut integrity
- Menthol demonstrates antimicrobial properties that may support gut health
SCIENTIFIC EVIDENCE
Betaine & Electrolyte Studies:
- A 2015 study by Sayed and Downing demonstrated that adding electrolyte-betaine supplements in feed or water improved feed conversion ratio (FCR), enhanced water consumption, and increased K⁺ and Na⁺ retention in heat-stressed broilers
- When using a diet with DEB of 180 mEq/kg, adding electrolyte-betaine supplements in drinking water was more beneficial than in feed
- Betaine supplementation at 500 mg/L improved BW gain during the first 4 days of heat exposure
- A 2011 study confirmed that oral rehydration fluids with betaine improved growth performance, water balance, and electrolyte retention in heat-stressed chicks
Menthol Cooling Effects:
- Menthol activates TRPM8 channels, triggering a cooling sensation; this mechanism is well-documented in scientific literature
- A 2022 master's thesis from Gyeongsang National University reported that in ovo feeding of 15 mg menthol significantly decreased rectal temperatures compared to control groups after heat stress exposure in broilers
- Menthol demonstrates anti-inflammatory and antioxidant properties that may help mitigate heat stress-induced oxidative damage
Comprehensive Heat Stress Review:
- A 2017 review by Saeed et al. confirmed that betaine acts as an osmolyte to maintain avian cellular water and ion balance, improving capacity against heat stress via preventing dehydration and osmotic inactivation
- Dietary betaine supplementation positively affects nutrient digestibility and protects internal organs
DOSAGE & ADMINISTRATION
MENTAQAS.PLUS is administered via drinking water. For optimal results, fresh medicated water should be prepared daily.
Recommended Dosage:
- Poultry (Broilers, Layers, Breeders, Turkeys, Ducks, Geese): 1-2 ml per liter of drinking water
- Severe Heat Stress or Dehydration: 2-3 ml per liter of drinking water for the first 24-48 hours
- Treatment Duration: 3-5 consecutive days, or as needed during stress periods
Recommended Usage Periods:
- Heat Stress: Administer during periods of high ambient temperature; continue throughout the hot period
- Vaccination: Administer 1-2 days before and 2-3 days after vaccination
- Disease Recovery: Administer during and for 3-5 days after antibiotic treatment
- Transport/Handling: Administer 1-2 days before and on the day of transport
Administration Guidelines:
- Calculate total daily water consumption based on flock size, age, and environmental temperature
- Dissolve the required amount of MENTAQAS.PLUS directly into the drinking water tank or mixing system
- For use in automatic water proportioners, adjust settings according to manufacturer specifications
- Prepare fresh medicated water daily; discard any unused solution after 24 hours
- For best results during heat stress, administer during the hottest parts of the day (midday to early afternoon)
CONTRAINDICATIONS & PRECAUTIONS
- Egg production: Safe for use in laying hens; no withdrawal period required for eggs
- Sensitive species: Use with caution in rabbits, hamsters, guinea pigs, or horses; consult a veterinarian before use
- Keep out of reach of children
- Store in a cool, dry place below 25°C, protected from direct sunlight
- Protect from freezing
- Shake well before use
- Use within 28 days after first opening
STORAGE
- Store in a cool, dry place below 25°C
- Protect from direct sunlight and freezing
- Keep container tightly closed when not in use
- Do not freeze
Target Species: Poultry (Broilers, Layers, Breeders, Turkeys, Ducks, Geese, Quail)
Pack Sizes: 1 Liter, 5 Liter HDPE containers
PRODUCT SUMMARY
MENTAQAS.PLUS Liquid Nutraceutical Betaine 100g, Sodium Chloride 20g, Magnesium Chloride 10g, Potassium Chloride 8g, Calcium Chloride 40g, Menthol per 100ml Poultry 1L,5L
FOR VETERINARY USE ONLY