A broad-spectrum anthelmintic oral suspension containing Fenbendazole with added Cobalt, Zinc, and Selenium for comprehensive treatment and control of gastrointestinal roundworms, lungworms, and tapeworms in livestock, while providing essential trace element supplementation for improved immunity, fertility, and hoof health.
Product Name: FENBENDAZONE
Type: Anthelmintic (Dewormer)
COMPOSITION
Each 100 ml contains:
- Fenbendazole USP ...... 12.5 g
- Cobalt Sulphate ...... 1.6 g
- Zinc Carbonate ...... 0.6 g
- Sodium Selenite USP ...... 3.0 g
- Excipients ...... q.s. to 100 ml
DESCRIPTION
FENBENDAZONE is a broad-spectrum anthelmintic oral suspension containing Fenbendazole, a potent benzimidazole compound, combined with the essential trace elements Cobalt, Zinc, and Selenium. This formulation provides comprehensive parasite control while simultaneously addressing trace mineral deficiencies that commonly affect livestock health and productivity [citation:3][citation:8].
Fenbendazole Mechanism of Action: Fenbendazole belongs to the benzimidazole (1-BZ) class of anthelmintics [citation:2][citation:7]. It acts by binding to the beta-tubulin within the microtubules of susceptible parasites, inhibiting their formation and disrupting cell division [citation:1]. This potent disruption inhibits the parasite's ability to produce energy (ATP), leading to paralysis and eventual death [citation:1]. What makes fenbendazole particularly safe is its selective affinity for parasite beta-tubulin over that of the host animal, meaning the animal's cells are not destroyed along with the parasites [citation:1].
Fenbendazole is effective against both adult and developing immature forms of gastrointestinal roundworms, lungworms, and tapeworms, and also exhibits ovicidal (egg-killing) activity, reducing pasture contamination [citation:2][citation:6].
Trace Elements (Cobalt, Zinc, Selenium):
- Cobalt is essential for rumen microbes to synthesize vitamin B12, which is critical for energy metabolism, red blood cell production, and appetite regulation [citation:3][citation:8].
- Zinc plays a vital role in immune function, skin integrity, hoof health, and the keratin lining of the teat canal, helping reduce the risk of mastitis and lameness [citation:3][citation:8].
- Selenium acts as a powerful antioxidant, working synergistically with vitamin E to support immune function, fertility, muscle development, and reduce the incidence of retained placenta and metritis [citation:3][citation:8].
Research has shown that organic trace mineral supplementation can improve feed intake, enhance selenium and cobalt status, lower the incidence of lameness by up to 50%, and reduce metabolic problems by up to 57% [citation:8].
INDICATIONS
FENBENDAZONE is indicated for the treatment and control of the following parasitic infections in livestock, with added benefits from trace element supplementation:
Gastrointestinal Roundworms (Nematodes):
- Ostertagia spp. (brown stomach worm) – including inhibited larvae [citation:2][citation:5]
- Haemonchus spp. (barber's pole worm) [citation:2][citation:5]
- Trichostrongylus spp. (black scour worm) [citation:2][citation:5]
- Cooperia spp. (small intestinal worm) [citation:2][citation:5]
- Nematodirus spp. (thread-necked intestinal worm) [citation:2][citation:5]
- Oesophagostomum spp. (nodular worm) [citation:2][citation:5]
- Bunostomum spp. (hookworm) [citation:2][citation:5]
- Chabertia spp. [citation:2]
- Strongyloides spp. [citation:2]
- Trichuris spp. (whipworm) [citation:2][citation:10]
Lungworms:
- Dictyocaulus viviparus (cattle lungworm) [citation:2][citation:5]
- Dictyocaulus filaria (sheep lungworm) [citation:2]
Tapeworms (Cestodes):
- Moniezia spp. [citation:2][citation:6]
ADDITIONAL BENEFITS OF TRACE ELEMENTS
In addition to parasite control, the Cobalt, Zinc, and Selenium in FENBENDAZONE provide essential nutritional support for:
- Improved Immune Function – Enhanced disease resistance and vaccine response [citation:3][citation:8]
- Better Fertility – Reduced days open and services per conception [citation:3][citation:8]
- Enhanced Hoof Health – Improved hoof quality and hardness, reduced lameness [citation:3][citation:8]
- Mastitis Prevention – Zinc supports teat canal keratin integrity [citation:3][citation:8]
- Optimal Growth – Improved feed intake and weight gain [citation:8]
- Reproductive Health – Selenium reduces retained placenta and metritis [citation:8]
DOSAGE & ADMINISTRATION
For oral administration only. Shake the container well before use. Use a properly calibrated drenching gun or dosing syringe for accurate administration. Body weight should be determined as accurately as possible to ensure proper dosage [citation:2].
Recommended Dosage:
| Species | Dosage | Equivalent |
|---|
| Cattle | 5 mg fenbendazole per kg body weight
(2.27 mg per lb) | 4 ml per 10 kg body weight [citation:2][citation:5] |
| Sheep | 5 mg fenbendazole per kg body weight
(2.27 mg per lb) | 4 ml per 10 kg body weight [citation:2] |
| Goats | 5 mg fenbendazole per kg body weight
(2.27 mg per lb) | 4 ml per 10 kg body weight [citation:5] |
Dosage Tables:
Cattle Dosage Guide:
| Body Weight (kg) | Dosage (ml) |
|---|
| 50 kg | 20 ml |
| 100 kg | 40 ml |
| 150 kg | 60 ml |
| 200 kg | 80 ml |
| 250 kg | 100 ml |
| 300 kg | 120 ml |
Sheep Dosage Guide:
| Body Weight (kg) | Dosage (ml) |
|---|
| Up to 15 kg | 6 ml |
| 16-25 kg | 10 ml |
| 26-35 kg | 14 ml |
| 36-50 kg | 20 ml |
| 51-65 kg | 26 ml |
| 66-75 kg | 30 ml |
WITHDRAWAL PERIODS
- Cattle (Meat): 14 days [citation:2][citation:6]
- Sheep (Meat): 21 days [citation:2]
- Goats (Meat): 6 days [citation:5]
- Cattle (Milk): 60-132 hours (approximately 3-6 days depending on formulation) [citation:2][citation:10]
- Sheep (Milk): Do not use in sheep producing milk for human consumption [citation:2]
- Goats (Milk): Do not use in lactating goats producing milk for human consumption [citation:5]
PRECAUTIONS & CONTRAINDICATIONS
- Do not use in animals with known hypersensitivity to fenbendazole or other benzimidazole anthelmintics [citation:2].
- Do not use in beef calves less than 2 months old, dairy calves, or veal calves [citation:5][citation:9].
- Do not use in pregnant animals during the first trimester unless absolutely necessary, as benzimidazoles may have teratogenic effects [citation:6].
- Resistance Warning: Frequent and repeated use of benzimidazole anthelmintics may lead to resistance. Implement strategic deworming programs with veterinary guidance and monitor efficacy through fecal egg count reduction tests [citation:2][citation:10].
- Drug Interactions: Do not use concurrently with bromsalan flukicides (e.g., dibromsalan, tribromsalan), as this combination has been reported to cause abortions in cattle and death in sheep [citation:7].
- Operator Safety: Avoid direct contact with skin. Wear impermeable rubber gloves during administration. Wash hands thoroughly after use. Do not eat, drink, or smoke while handling this product. In case of accidental ingestion, seek medical advice immediately [citation:2].
- Environmental Precautions: DANGEROUS to aquatic life. Do not contaminate ponds, waterways, or ditches with the product or used containers [citation:2].
- Store in a cool, dry place below 25-30°C, protected from light. Do not freeze [citation:2][citation:5].
- Keep out of reach of children.
Target Species: Cattle, Sheep, Goats
Pack Sizes: 1 Liter
PRODUCT SUMMARY
FENBENDAZONE Liquid Anthelmintic (Dewormer) Each 100 ml Contains: Fenbendazole USP…………… 12.5 gm Cobalt Sulphate ……………… 1.6 gm Zinc Carbonate ………………. 0.6 gm Sodium Selenite USP……..…….. 3.0 gm Livestock 1 Liter
FOR VETERINARY USE ONLY
