Product Name: QASTOX PLATINUM

Type: Yeast-Based Toxin Binder (Feed Additive Powder)

COMPOSITION

• Mannan-Oligosaccharides (MOS) – from Saccharomyces cerevisiae yeast cell wall
• Bentonite-Montmorillonite – aluminosilicate clay
• Oils
• Artichoke Extract – (Cynara scolymus)

DESCRIPTION

QASTOX PLATINUM is a next-generation yeast-based mycotoxin binder that combines the broad-spectrum adsorption capabilities of clay minerals with the specific binding properties of yeast cell wall components, enhanced by artichoke extract for liver support. This multi-component formulation is designed to address the complex challenge of multi-mycotoxin contamination in animal feed

Mannan-Oligosaccharides (MOS): MOS are derived from the cell wall of Saccharomyces cerevisiae yeast. The yeast cell wall is rich in mannoproteins, β-glucans, and chitin, with β-glucans accounting for roughly 30% of the dry weight

Research has demonstrated that glucomannan binds aflatoxin (AF) at high rates of 85-96% . However, its binding capacity for deoxynivalenol (DON) ranges from 31-56% and for ochratoxin (OTA) from 54-55% . MOS also binds other mycotoxins such as zearalenone, fumonisins, and T-2 toxin at rates of 25-43%

Bentonite-Montmorillonite: These aluminosilicate clays are highly effective at binding polar mycotoxins, particularly aflatoxins. Studies have shown that bentonite binds aflatoxin at rates of 88-95% and DON at 23-73%, while montmorillonite binds AF at 74-80% and DON at 46-68%

Synergistic Combination: The combination of clays with glucomannan has been shown to significantly increase binding efficacy against certain mycotoxins. Research indicates that when glucomannan is added to clay combinations, the resulting product demonstrates enhanced ability to bind ochratoxin (OTA), fumonisin (FUM), and T-2 toxin by approximately 15-20% compared to clay alone . Similarly, such combinations provide >10% greater adsorption of aflatoxin, 20% greater adsorption of OTA and FUM, and 5% greater adsorption of T-2 toxin compared to some commercial products

Artichoke Extract: Artichoke (Cynara scolymus) leaves supply cynarin, phenolic acids, and flavonoids with hepatoprotective (liver-protecting), anti-inflammatory, and antioxidant properties

When used alongside adsorbents, artichoke extract supports liver detoxification pathways and helps counter the oxidative stress triggered by mycotoxin exposure . This is particularly important because mycotoxins like aflatoxins primarily target the liver, causing hepatocellular damage and impairing metabolic function

INDICATIONS
QASTOX PLATINUM is indicated for the prevention and management of mycotoxicosis in livestock and poultry, specifically targeting:

• Aflatoxins (AF) – Highly carcinogenic; bentonite-clay combination provides 88-98% binding efficacy
• Ochratoxin A (OTA) – Nephrotoxic; yeast-clay combination enhances binding by 15-20%
• Zearalenone (ZEA) – Estrogenic effects; binding rates of 25-45% with enhanced efficacy from combination
• Deoxynivalenol (DON/Vomitoxin) – Reduced feed intake; binding rates of 23-73%
• Fumonisins (FUM) – Immunosuppressive; combination provides up to 20% enhanced binding
• T-2 Toxin & HT-2 Toxin – Trichothecenes affecting immunity and growth; enhanced binding with yeast-clay combination

EFFICACY DATA

Published research on clay-glucomannan combinations (2022) has demonstrated the following binding capacities at physiological pH conditions (pH 3.0 and 6.8) :

ADDITIONAL BENEFITS

• β-Glucans – Act as immune modulators, enhancing non-specific immune responses
• Artichoke Extract (Cynarin) – Supports liver regeneration, enhances bile flow, and reduces oxidative damage induced by toxins
• Hepatoprotective Action – Helps minimize residual toxin impact on liver function
• Gut Health Support – MOS can agglutinate pathogens, improve villus height, and bolster intestinal integrity
• Antioxidant Properties – Artichoke flavonoids counter oxidative stress from mycotoxins

DOSAGE & ADMINISTRATION

For inclusion in complete feed. Thorough mixing is essential to ensure uniform distribution of the binder throughout the feed.

Recommended Inclusion Rates:

Administration Guidelines:

• Mix thoroughly into the complete feed using a progressive mixer to ensure uniform distribution
• Higher inclusion rates should be used when mycotoxin contamination levels are confirmed or suspected
• Continuous use is recommended in areas with high mycotoxin risk

PRECAUTIONS & SELECTIVITY CONSIDERATIONS

• The combination of clay and yeast components in this product helps balance adsorption efficacy while minimizing potential nutrient interactions
• Studies show that mycotoxin binders may adsorb certain vitamins (E, B1, B2, B6) and amino acids (lysine, methionine, threonine) when used at high concentrations
• The addition of MOS and artichoke extract helps offset potential nutrient interactions through enhanced gut health and nutrient absorption
• Store in a cool, dry place below 25-30°C, protected from moisture
• Use within 6 months of opening for optimal efficacy
• Keep out of reach of children.

Target Species: Poultry, Swine, Cattle, Sheep, Goats

Pack Sizes: 25 kg

PRODUCT SUMMARY
QASTOX PLATINUM (Yeast Based Toxin Binder) Feed Additive Powder Mannan-oligosaccharides, bentonite-montmorillonite, oil and artichoke extract Livestock 25kg

FOR VETERINARY USE ONLY