Product Name: Fosfozone Powder

COMPOSITION
Each 100 gm powder contains:

• Fosfomycin Calcium BP ................ 20 gm
• Tylosin Tartrate USP ........................ 10 gm
• Fructose USP ................................... 18 gm
• Sodium Phosphate USP .................... 15 gm
• Magnesium Sulphate USP .................. 10 gm
  (Product complies with innovator specs)

DESCRIPTION

Fosfomycin is an antibiotic produced by Streptomyces fradiae and classified under the Phosphonic Acids group of organic antibiotics. It has a broad spectrum antimicrobial activity and acts as a bactericidal agent against most aerobic Gram-negative and Gram-positive bacteria such as E. coli, Pasteurella, Staphylococcus, Salmonella, Pseudomonas, etc. Fosfomycin has a unique mechanism of action in which it irreversibly inhibits an early stage of bacterial cell wall biosynthesis.

Tylosin is a macrolide antibiotic with bacteriostatic action, interfering with protein synthesis and inhibiting the transpeptidation and translocation process in the bacterial cell. Tylosin is active against Mycoplasma, Gram-positive bacteria, and cocci. It has a synergistic effect with Fosfomycin, improving the therapeutic effect of the product.

Fructose is an auxiliary energy source that helps animals recuperate from disease, helping them to continue eating while recovering. It acts as a vehicle for the transport of the active ingredients, allowing the antibiotic to enter the bacterial cell and reach the target area more quickly.

Electrolytes play an important role in the rehydration process of sick birds, especially for day-old chicks arriving from the hatchery due to changes in humidity.

INDICATIONS

For Poultry:
Fosfozone is indicated for infections of the respiratory and digestive tract, especially those produced by:

• E. coli and Salmonella spp.
• Mycoplasmosis
• Chronic Respiratory Disease (CRD) Complex
• Fowl Cholera
• Infectious Coryza
• Avian Typhoid
• Staphylococcal infections
• Secondary bacterial infections as a consequence of viral diseases

DOSAGE AND ADMINISTRATION
For oral administration:

• 160 mg Fosfozone per kg body weight daily, approximately equivalent to 500-800 g per 1000 liters of drinking water.
• Administer for 3 to 7 consecutive days.
• Medicated drinking water should be used within 24 hours.

PACKING
Jar of 500 g & 1000 g

STORAGE CONDITIONS

• Store below 30°C in a cool and dry place.
• Store in closed packaging.
• Keep medicine away from children.

WITHDRAWAL PERIOD

• Meat: 3 days
• Do not use in laying hens producing eggs for human consumption.

FOR VETERINARY USE ONLY